Since I have a lifetime membership to Champions online, I was able to get into the beta weekend for Neverwinter. After playing for 10 minutes, I created a Neverwinter Logitech g13 profile. The layout is simple because Neverwinters controls are simple. This isn’t much more than I would normally do for an FPS keyboard layout with movement and the dailies. I have found that this works very well for the Guardian, rogue, and healer character classes. I havent played a fighter or mage yet, but I think it will still work.
Below is a screenshot of the keyboard layout.